Naturally processed T cell epitopes from human glutamic acid decarboxylase identified using mice transgenic for the type 1 diabetes-associated human MHC class II allele, DRB1*0401. [electronic resource]
- The Journal of clinical investigation Dec 1996
- 2597-603 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0021-9738
10.1172/JCI119079 doi
Alleles Amino Acid Sequence Animals Autoantibodies--analysis B-Lymphocytes--immunology Cell Line Diabetes Mellitus, Type 1--genetics Epitopes--analysis Genes, MHC Class II Glutamate Decarboxylase--biosynthesis HLA-DR Antigens--biosynthesis HLA-DRB1 Chains Humans Lymphocyte Activation Mice Mice, Inbred NOD Mice, Transgenic Molecular Sequence Data Peptide Fragments--chemistry Recombinant Proteins--biosynthesis T-Lymphocytes--immunology