TY  - GEN
AU  - Zhao,Z
AU  - Koeplinger,K A
AU  - Padbury,G E
AU  - Hauer,M J
AU  - Bundy,G L
AU  - Banitt,L S
AU  - Schwartz,T M
AU  - Zimmermann,D C
AU  - Harbach,P R
AU  - Mayo,J K
AU  - Aaron,C S
TI  - Bioactivation of 6,7-dimethyl-2,4-di-1-pyrrolidinyl-7H-pyrrolo[2,3-d]pyrimidine (U-89843) to reactive intermediates that bind covalently to macromolecules and produce genotoxicity
SN  - 0893-228X
PY  - 1997///0317
KW  - Animals
KW  - Biotransformation
KW  - Chromatography, High Pressure Liquid
KW  - DNA Repair
KW  - Dogs
KW  - Free Radical Scavengers
KW  - chemistry
KW  - Gas Chromatography-Mass Spectrometry
KW  - Haplorhini
KW  - Humans
KW  - In Vitro Techniques
KW  - Male
KW  - Microsomes, Liver
KW  - metabolism
KW  - Mutagens
KW  - Protein Binding
KW  - Pyrimidines
KW  - Pyrroles
KW  - Rats
KW  - Rats, Inbred F344
KW  - Spectrometry, Mass, Fast Atom Bombardment
KW  - Spectrophotometry, Ultraviolet
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1021/tx960092z
ER  -