Zhao, Z <br/><br/>
Bioactivation of 6,7-dimethyl-2,4-di-1-pyrrolidinyl-7H-pyrrolo[2,3-d]pyrimidine (U-89843) to reactive intermediates that bind covalently to macromolecules and produce genotoxicity.  [electronic resource] 

 -  Chemical research in toxicology  Dec 1996 
 - 1230-9 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>0893-228X 
<br/><br/><label>Standard No.: </label>10.1021/tx960092z  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Biotransformation<br/>Chromatography, High Pressure Liquid<br/>DNA Repair<br/>Dogs<br/>Free Radical Scavengers--chemistry<br/>Gas Chromatography-Mass Spectrometry<br/>Haplorhini<br/>Humans<br/>In Vitro Techniques<br/>Male<br/>Microsomes, Liver--metabolism<br/>Mutagens--chemistry<br/>Protein Binding<br/>Pyrimidines--chemistry<br/>Pyrroles--chemistry<br/>Rats<br/>Rats, Inbred F344<br/>Spectrometry, Mass, Fast Atom Bombardment<br/>Spectrophotometry, Ultraviolet