TY  - GEN
AU  - Dunn,W J
AU  - Hopfinger,A J
AU  - Catana,C
AU  - Duraiswami,C
TI  - Solution of the conformation and alignment tensors for the binding of trimethoprim and its analogs to dihydrofolate reductase: 3D-quantitative structure-activity relationship study using molecular shape analysis, 3-way partial least-squares regression, and 3-way factor analysis
SN  - 0022-2623
PY  - 1997///0106
KW  - Chemical Phenomena
KW  - Chemistry
KW  - Crystallography, X-Ray
KW  - Drug Design
KW  - Enzyme Inhibitors
KW  - chemistry
KW  - Escherichia coli
KW  - enzymology
KW  - Folic Acid Antagonists
KW  - Molecular Conformation
KW  - Molecular Structure
KW  - Structure-Activity Relationship
KW  - Tetrahydrofolate Dehydrogenase
KW  - Trimethoprim
KW  - analogs & derivatives
N1  - Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S
UR  - https://doi.org/10.1021/jm960491r
ER  -