TY  - GEN
AU  - Bharadwaj,D
AU  - Iino,M
AU  - Kontoyianni,M
AU  - Smith,K J
AU  - Foster,D C
AU  - Kisiel,W
TI  - Factor VII central. A novel mutation in the catalytic domain that reduces tissue factor binding, impairs activation by factor Xa, and abolishes amidolytic and coagulant activity
SN  - 0021-9258
PY  - 1997///0107
KW  - Adult
KW  - Aspartic Acid
KW  - chemistry
KW  - Blood Coagulation Disorders
KW  - genetics
KW  - Factor VII
KW  - Factor Xa
KW  - metabolism
KW  - Humans
KW  - Hydrogen Bonding
KW  - Male
KW  - Models, Molecular
KW  - Point Mutation
KW  - Recombinant Proteins
KW  - Structure-Activity Relationship
KW  - Thromboplastin
KW  - Tyrosine
N1  - Publication Type: Case Reports; Journal Article; Research Support, U.S. Gov't, P.H.S
UR  - https://doi.org/10.1074/jbc.271.48.30685
ER  -