Bharadwaj, D <br/><br/>
Factor VII central. A novel mutation in the catalytic domain that reduces tissue factor binding, impairs activation by factor Xa, and abolishes amidolytic and coagulant activity.  [electronic resource] 

 -  The Journal of biological chemistry  Nov 1996 
 - 30685-91 p.  digital 
<br/><br/> Publication Type: Case Reports; Journal Article; Research Support, U.S. Gov't, P.H.S. 
<br/><br/><label>ISSN: </label>0021-9258 
<br/><br/><label>Standard No.: </label>10.1074/jbc.271.48.30685  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Adult<br/>Aspartic Acid--chemistry<br/>Blood Coagulation Disorders--genetics<br/>Factor VII--chemistry<br/>Factor Xa--metabolism<br/>Humans<br/>Hydrogen Bonding<br/>Male<br/>Models, Molecular<br/>Point Mutation<br/>Recombinant Proteins<br/>Structure-Activity Relationship<br/>Thromboplastin--metabolism<br/>Tyrosine--chemistry