TY  - GEN
AU  - He,Y Q
AU  - Szklarz,G D
AU  - Halpert,J R
TI  - Interconversion of the androstenedione hydroxylase specificities of cytochromes P450 2B4 and 2B5 upon simultaneous site-directed mutagenesis of four key substrate recognition residues
SN  - 0003-9861
PY  - 1996///1224
KW  - Androstenedione
KW  - metabolism
KW  - Animals
KW  - Aryl Hydrocarbon Hydroxylases
KW  - Base Sequence
KW  - Binding Sites
KW  - Cloning, Molecular
KW  - Cytochrome P-450 Enzyme System
KW  - chemistry
KW  - Cytochrome P450 Family 2
KW  - DNA Primers
KW  - Escherichia coli
KW  - Models, Molecular
KW  - Molecular Sequence Data
KW  - Mutagenesis, Site-Directed
KW  - Oxazines
KW  - Point Mutation
KW  - Polymerase Chain Reaction
KW  - Progesterone
KW  - Protein Conformation
KW  - Rabbits
KW  - Recombinant Proteins
KW  - Steroid 16-alpha-Hydroxylase
KW  - Steroid Hydroxylases
KW  - Substrate Specificity
N1  - Publication Type: Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S
UR  - https://doi.org/10.1006/abbi.1996.0493
ER  -