TY  - GEN
AU  - Lyons,T J
AU  - Liu,H
AU  - Goto,J J
AU  - Nersissian,A
AU  - Roe,J A
AU  - Graden,J A
AU  - Café,C
AU  - Ellerby,L M
AU  - Bredesen,D E
AU  - Gralla,E B
AU  - Valentine,J S
TI  - Mutations in copper-zinc superoxide dismutase that cause amyotrophic lateral sclerosis alter the zinc binding site and the redox behavior of the protein
SN  - 0027-8424
PY  - 1996///1224
KW  - Amyotrophic Lateral Sclerosis
KW  - enzymology
KW  - Binding Sites
KW  - Cobalt
KW  - metabolism
KW  - Copper
KW  - Electron Spin Resonance Spectroscopy
KW  - Humans
KW  - Hydrogen-Ion Concentration
KW  - Mutagenesis, Site-Directed
KW  - Oxidation-Reduction
KW  - Polymerase Chain Reaction
KW  - Spectrophotometry, Ultraviolet
KW  - Superoxide Dismutase
KW  - genetics
KW  - Zinc
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S
UR  - https://doi.org/10.1073/pnas.93.22.12240
ER  -