TY  - GEN
AU  - Feierman,D E
AU  - Lasker,J M
TI  - Metabolism of fentanyl, a synthetic opioid analgesic, by human liver microsomes. Role of CYP3A4
SN  - 0090-9556
PY  - 1997///0212
KW  - Analgesics, Opioid
KW  - metabolism
KW  - Aryl Hydrocarbon Hydroxylases
KW  - Cytochrome P-450 CYP1A2
KW  - Cytochrome P-450 CYP2C8
KW  - Cytochrome P-450 CYP2C9
KW  - Cytochrome P-450 CYP3A
KW  - Cytochrome P-450 Enzyme Inhibitors
KW  - Cytochrome P-450 Enzyme System
KW  - Fentanyl
KW  - analogs & derivatives
KW  - Gas Chromatography-Mass Spectrometry
KW  - Humans
KW  - Ketoconazole
KW  - pharmacology
KW  - Kinetics
KW  - Microsomes, Liver
KW  - enzymology
KW  - Mixed Function Oxygenases
KW  - antagonists & inhibitors
KW  - Steroid 16-alpha-Hydroxylase
KW  - Steroid Hydroxylases
KW  - Theophylline
KW  - Tolbutamide
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S
ER  -