TY  - GEN
AU  - Whitcomb,D C
AU  - Gorry,M C
AU  - Preston,R A
AU  - Furey,W
AU  - Sossenheimer,M J
AU  - Ulrich,C D
AU  - Martin,S P
AU  - Gates,L K
AU  - Amann,S T
AU  - Toskes,P P
AU  - Liddle,R
AU  - McGrath,K
AU  - Uomo,G
AU  - Post,J C
AU  - Ehrlich,G D
TI  - Hereditary pancreatitis is caused by a mutation in the cationic trypsinogen gene
SN  - 1061-4036
PY  - 1996///1112
KW  - Arginine
KW  - physiology
KW  - Chromosomes, Human, Pair 7
KW  - DNA Mutational Analysis
KW  - Enzyme Activation
KW  - Exons
KW  - genetics
KW  - Female
KW  - Genes
KW  - Heterozygote
KW  - Humans
KW  - Male
KW  - Models, Molecular
KW  - Pancreatitis
KW  - Pedigree
KW  - Point Mutation
KW  - Polymorphism, Restriction Fragment Length
KW  - Protein Conformation
KW  - Protein Structure, Tertiary
KW  - Trypsin
KW  - metabolism
KW  - Trypsinogen
KW  - chemistry
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S
UR  - https://doi.org/10.1038/ng1096-141
ER  -