Montano, M M

Human estrogen receptor ligand activity inversion mutants: receptors that interpret antiestrogens as estrogens and estrogens as antiestrogens and discriminate among different antiestrogens. [electronic resource] - Molecular endocrinology (Baltimore, Md.) Mar 1996 - 230-42 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0888-8809

10.1210/mend.10.3.8833652 doi


3T3 Cells--drug effects
Animals
Breast Neoplasms--pathology
CHO Cells--drug effects
Cricetinae
Cricetulus
Estradiol--analogs & derivatives
Estrogen Antagonists--classification
Estrogens--metabolism
Female
Humans
Ligands
Mice
Neoplasms, Hormone-Dependent--pathology
Point Mutation
Polyunsaturated Alkamides
Promoter Regions, Genetic
Protein Binding
Receptors, Estrogen--drug effects
Recombinant Fusion Proteins--biosynthesis
Structure-Activity Relationship
Substrate Specificity
Tamoxifen--analogs & derivatives
Transcription, Genetic
Tumor Cells, Cultured--drug effects