TY - GEN AU - Kakkis,E D AU - McEntee,M F AU - Schmidtchen,A AU - Neufeld,E F AU - Ward,D A AU - Gompf,R E AU - Kania,S AU - Bedolla,C AU - Chien,S L AU - Shull,R M TI - Long-term and high-dose trials of enzyme replacement therapy in the canine model of mucopolysaccharidosis I SN - 1077-3150 PY - 1996///1101 KW - Animals KW - Antibody Formation KW - Brain KW - drug effects KW - Brain Chemistry KW - Cartilage KW - Disease Models, Animal KW - Dogs KW - Dose-Response Relationship, Drug KW - Female KW - Glycosaminoglycans KW - metabolism KW - Humans KW - Iduronidase KW - Lysosomes KW - Male KW - Mucopolysaccharidosis I KW - drug therapy KW - Recombinant Proteins KW - immunology KW - Tissue Distribution N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1006/bmme.1996.0044 ER -