Kakkis, E D <br/><br/>
Long-term and high-dose trials of enzyme replacement therapy in the canine model of mucopolysaccharidosis I.  [electronic resource] 

 -  Biochemical and molecular medicine  Aug 1996 
 - 156-67 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. 
<br/><br/><label>ISSN: </label>1077-3150 
<br/><br/><label>Standard No.: </label>10.1006/bmme.1996.0044  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Antibody Formation<br/>Brain--drug effects<br/>Brain Chemistry<br/>Cartilage--drug effects<br/>Disease Models, Animal<br/>Dogs<br/>Dose-Response Relationship, Drug<br/>Female<br/>Glycosaminoglycans--metabolism<br/>Humans<br/>Iduronidase--metabolism<br/>Lysosomes--metabolism<br/>Male<br/>Mucopolysaccharidosis I--drug therapy<br/>Recombinant Proteins--immunology<br/>Tissue Distribution