TY - GEN AU - Hung,D T AU - Chen,J AU - Schreiber,S L TI - (+)-Discodermolide binds to microtubules in stoichiometric ratio to tubulin dimers, blocks taxol binding and results in mitotic arrest SN - 1074-5521 PY - 1997///0204 KW - 3T3 Cells KW - Alkanes KW - Animals KW - Binding Sites KW - Carbamates KW - Cell Line KW - Humans KW - Lactones KW - metabolism KW - Mice KW - Microtubules KW - Mitosis KW - drug effects KW - Paclitaxel KW - antagonists & inhibitors KW - Pyrones N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1016/s1074-5521(96)90108-8 ER -