Hung, D T <br/><br/>
(+)-Discodermolide binds to microtubules in stoichiometric ratio to tubulin dimers, blocks taxol binding and results in mitotic arrest.  [electronic resource] 

 -  Chemistry & biology  Apr 1996 
 - 287-93 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. 
<br/><br/><label>ISSN: </label>1074-5521 
<br/><br/><label>Standard No.: </label>10.1016/s1074-5521(96)90108-8  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>3T3 Cells<br/>Alkanes<br/>Animals<br/>Binding Sites<br/>Carbamates<br/>Cell Line<br/>Humans<br/>Lactones--metabolism<br/>Mice<br/>Microtubules--metabolism<br/>Mitosis--drug effects<br/>Paclitaxel--antagonists & inhibitors<br/>Pyrones