Chronic exposure of LLC-PK1 epithelia to the phorbol ester TPA produces polyp-like foci with leaky tight junctions and altered protein kinase C-alpha expression and localization. [electronic resource]
- Experimental cell research Aug 1996
- 12-22 p. digital
Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
0014-4827
10.1006/excr.1996.0244 doi
Animals Carcinoma Cell Membrane--enzymology Cell Membrane Permeability--drug effects Cell Transformation, Neoplastic--pathology Clone Cells Coloring Agents Cytosol--enzymology Electric Impedance Epithelial Cells Epithelium--enzymology Isoenzymes--analysis LLC-PK1 Cells--drug effects Mannitol--metabolism Protein Kinase C--analysis Protein Kinase C-alpha Ruthenium Red Swine Tetradecanoylphorbol Acetate--pharmacology Tight Junctions--drug effects