Yu, L

Abnormal regulation of the LDL-R and HMG CoA reductase genes in subjects with familial hypercholesterolemia with the "French Canadian mutation". [electronic resource] - Atherosclerosis Jul 1996 - 103-17 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0021-9150

10.1016/0021-9150(96)05828-5 doi


Anticholesteremic Agents--pharmacology
Canada--epidemiology
Cells, Cultured
Enzyme Induction
Enzyme Inhibitors--pharmacology
Ethnicity--genetics
Female
Fibroblasts--metabolism
France--ethnology
Gene Expression Regulation--drug effects
Haploidy
Humans
Hydroxymethylglutaryl CoA Reductases--genetics
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Hyperlipoproteinemia Type II--drug therapy
Lipoproteins, LDL--metabolism
Lovastatin--pharmacology
Male
Prevalence
RNA, Messenger--biosynthesis
Receptors, LDL--genetics
Sequence Deletion
Transcription, Genetic
Treatment Failure