Tohkin, M

Okadaic acid potentiates 3-methylcholanthrene-induced CYP2A8 gene expression in primary cultures of Syrian hamster hepatocytes: possible involvement of activator protein-1. [electronic resource] - Molecular pharmacology Sep 1996 - 556-64 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0026-895X


Animals
Anisomycin--pharmacology
Aryl Hydrocarbon Hydroxylases
Base Sequence
Cell Nucleus--metabolism
Cells, Cultured
Colforsin--pharmacology
Consensus Sequence
Cricetinae
Cycloheximide--pharmacology
Cytochrome P-450 CYP2A6
Cytochrome P-450 Enzyme System--biosynthesis
Cytochrome P450 Family 2
Dexamethasone--pharmacology
Dose-Response Relationship, Drug
Enzyme Induction--drug effects
Enzyme Inhibitors--pharmacology
Female
Genes, fos
Genes, jun
Kinetics
Liver--enzymology
Mesocricetus
Methylcholanthrene--pharmacology
Mixed Function Oxygenases--biosynthesis
Molecular Sequence Data
Okadaic Acid--pharmacology
Oligodeoxyribonucleotides
Phosphoprotein Phosphatases--antagonists & inhibitors
Proto-Oncogene Proteins c-fos--biosynthesis
Proto-Oncogene Proteins c-jun--biosynthesis
RNA, Messenger--biosynthesis
Transcription Factor AP-1--metabolism
Transcription, Genetic--drug effects