Nonpeptidal P2 ligands for HIV protease inhibitors: structure-based design, synthesis, and biological evaluation. [electronic resource]
- Journal of medicinal chemistry Aug 1996
- 3278-90 p. digital
Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
0022-2623
10.1021/jm960128k doi
Amino Acid Sequence Aspartic Acid Binding Sites Crystallography, X-Ray Drug Design Furans--chemical synthesis HIV Protease--chemistry HIV Protease Inhibitors--chemical synthesis HIV-1--enzymology Hydrogen Bonding Ligands Magnetic Resonance Spectroscopy Models, Molecular Molecular Structure Optical Rotation Stereoisomerism Structure-Activity Relationship