TY - GEN AU - Bories,J C AU - Demengeot,J AU - Davidson,L AU - Alt,F W TI - Gene-targeted deletion and replacement mutations of the T-cell receptor beta-chain enhancer: the role of enhancer elements in controlling V(D)J recombination accessibility SN - 0027-8424 PY - 1996///1029 KW - Alleles KW - Animals KW - B-Lymphocytes KW - immunology KW - Base Sequence KW - Blastocyst KW - Cells, Cultured KW - Chimera KW - DNA Nucleotidyltransferases KW - metabolism KW - DNA Primers KW - DNA-Binding Proteins KW - Enhancer Elements, Genetic KW - Gene Deletion KW - Gene Rearrangement, beta-Chain T-Cell Antigen Receptor KW - Genetic Complementation Test KW - Genomic Library KW - Immunoglobulin Heavy Chains KW - genetics KW - Immunoglobulin Joining Region KW - biosynthesis KW - Immunoglobulin Variable Region KW - Mice KW - Molecular Sequence Data KW - Polymerase Chain Reaction KW - Proteins KW - Receptors, Antigen, T-Cell, alpha-beta KW - Restriction Mapping KW - Sequence Deletion KW - Spleen KW - Stem Cells KW - Transcription, Genetic KW - VDJ Recombinases N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1073/pnas.93.15.7871 ER -