Cardiotoxic and drug interaction profile of the second generation antihistamines ebastine and terfenadine in an experimental animal model of torsade de pointes. [electronic resource]
- Arzneimittel-Forschung Feb 1996
- 159-63 p. digital
Publication Type: Journal Article
0004-4172
Animals Butyrophenones--toxicity Cytochrome P-450 CYP3A Cytochrome P-450 Enzyme System--metabolism Drug Interactions Electrocardiography--drug effects Guinea Pigs Heart Diseases--chemically induced Histamine H1 Antagonists--toxicity Ketoconazole--pharmacology Liver--enzymology Male Mixed Function Oxygenases--metabolism Piperidines--toxicity Terfenadine--toxicity Torsades de Pointes--chemically induced