Hey, J A

Cardiotoxic and drug interaction profile of the second generation antihistamines ebastine and terfenadine in an experimental animal model of torsade de pointes. [electronic resource] - Arzneimittel-Forschung Feb 1996 - 159-63 p. digital

Publication Type: Journal Article

0004-4172


Animals
Butyrophenones--toxicity
Cytochrome P-450 CYP3A
Cytochrome P-450 Enzyme System--metabolism
Drug Interactions
Electrocardiography--drug effects
Guinea Pigs
Heart Diseases--chemically induced
Histamine H1 Antagonists--toxicity
Ketoconazole--pharmacology
Liver--enzymology
Male
Mixed Function Oxygenases--metabolism
Piperidines--toxicity
Terfenadine--toxicity
Torsades de Pointes--chemically induced