TY - GEN AU - Picksley,S M AU - Spicer,J F AU - Barnes,D M AU - Lane,D P TI - The p53-MDM2 interaction in a cancer-prone family, and the identification of a novel therapeutic target SN - 0284-186X PY - 1996///0903 KW - Antineoplastic Agents KW - chemical synthesis KW - Breast Neoplasms KW - drug therapy KW - Carcinoma in Situ KW - genetics KW - Carcinoma, Ductal, Breast KW - Cell Division KW - Cyclin-Dependent Kinase Inhibitor p21 KW - Cyclins KW - Drug Design KW - Enzyme Inhibitors KW - metabolism KW - Female KW - Gene Expression Regulation, Neoplastic KW - Genes, p53 KW - Humans KW - Leiomyosarcoma KW - Neoplasm Proteins KW - Neoplasm Recurrence, Local KW - Neoplasms, Second Primary KW - Nuclear Proteins KW - Phenotype KW - Protein Binding KW - Proto-Oncogene Proteins KW - Proto-Oncogene Proteins c-mdm2 KW - Proto-Oncogenes KW - Soft Tissue Neoplasms KW - Transcription, Genetic KW - Tumor Suppressor Protein p53 N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.3109/02841869609109917 ER -