TY  - GEN
AU  - Parr,I B
AU  - Boehlein,S K
AU  - Dribben,A B
AU  - Schuster,S M
AU  - Richards,N G
TI  - Mapping the aspartic acid binding site of Escherichia coli asparagine synthetase B using substrate analogs
SN  - 0022-2623
PY  - 1996///0823
KW  - Alkylation
KW  - Antineoplastic Agents
KW  - chemistry
KW  - Asparagine
KW  - biosynthesis
KW  - Aspartate-Ammonia Ligase
KW  - antagonists & inhibitors
KW  - Aspartic Acid
KW  - analogs & derivatives
KW  - Bacterial Proteins
KW  - Binding Sites
KW  - Drug Design
KW  - Enzyme Inhibitors
KW  - chemical synthesis
KW  - Escherichia coli
KW  - enzymology
KW  - Glutamine
KW  - metabolism
KW  - Humans
KW  - Isoenzymes
KW  - Kinetics
KW  - Molecular Conformation
KW  - Molecular Structure
KW  - Neoplasm Proteins
KW  - Precursor Cell Lymphoblastic Leukemia-Lymphoma
KW  - drug therapy
KW  - Protein Binding
KW  - Stereoisomerism
KW  - Structure-Activity Relationship
KW  - Substrate Specificity
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S
UR  - https://doi.org/10.1021/jm9601009
ER  -