Design, synthesis, and biological activities of cyclic lactam peptide analogues of dynorphine A(1-11)-NH2. [electronic resource]
- Journal of medicinal chemistry Mar 1996
- 1136-41 p. digital
Publication Type: Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.
0022-2623
10.1021/jm950369c doi
Amino Acid Sequence Animals Brain--metabolism Cell Membrane--metabolism Cyclization Drug Design Dynorphins--chemistry Guinea Pigs Ileum--physiology Lactams--chemical synthesis Male Molecular Sequence Data Muscle Contraction--drug effects Peptide Fragments--chemical synthesis Protein Conformation Protein Structure, Secondary Receptors, Opioid, kappa--drug effects Structure-Activity Relationship