TY - GEN AU - Ricci,G AU - Caccuri,A M AU - Lo Bello,M AU - Rosato,N AU - Mei,G AU - Nicotra,M AU - Chiessi,E AU - Mazzetti,A P AU - Federici,G TI - Structural flexibility modulates the activity of human glutathione transferase P1-1. Role of helix 2 flexibility in the catalytic mechanism SN - 0021-9258 PY - 1996///0829 KW - Binding Sites KW - Catalysis KW - Cysteine KW - Dinitrochlorobenzene KW - metabolism KW - Female KW - Glutathione Transferase KW - chemistry KW - Humans KW - Isoenzymes KW - Kinetics KW - Mathematics KW - Models, Structural KW - Models, Theoretical KW - Mutagenesis, Site-Directed KW - Placenta KW - enzymology KW - Point Mutation KW - Pregnancy KW - Protein Structure, Secondary KW - Recombinant Proteins KW - Spectrometry, Fluorescence KW - Viscosity N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1074/jbc.271.27.16187 ER -