Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis. [electronic resource]
- Proceedings of the National Academy of Sciences of the United States of America Apr 1996
- 3444-9 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
0027-8424
10.1073/pnas.93.8.3444 doi
Animals Base Sequence Central Nervous System Diseases--genetics Core Binding Factor Alpha 2 Subunit DNA Primers--genetics DNA, Complementary--genetics DNA-Binding Proteins Erythropoiesis--genetics Female Fetal Death--genetics Gene Targeting Hematopoiesis--genetics Hemorrhage--genetics Humans Mice Mice, Inbred BALB C Mice, Inbred C57BL Molecular Sequence Data Mutation Necrosis Neoplasm Proteins--genetics Pregnancy Proto-Oncogene Proteins Proto-Oncogenes Transcription Factors--genetics