TY - GEN AU - Mhashilkar,A M AU - Viswanatha,T AU - Chibber,B A AU - Castellino,F J TI - Breaching the conformational integrity of the catalytic triad of the serine protease plasmin: localized disruption of a side chain of His-603 strongly inhibits the amidolytic activity of human plasmin SN - 0027-8424 PY - 1993///0707 KW - Amino Acid Sequence KW - Animals KW - Baculoviridae KW - genetics KW - Base Sequence KW - Cell Line KW - Chromatography, Affinity KW - Fibrinolysin KW - chemistry KW - Histidine KW - Humans KW - Imidazoles KW - pharmacology KW - Isoflurophate KW - Kinetics KW - Molecular Sequence Data KW - Moths KW - Mutagenesis, Site-Directed KW - Oligodeoxyribonucleotides KW - Proline KW - Protein Conformation KW - Recombinant Proteins KW - Transfection N1 - Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1073/pnas.90.11.5374 ER -