Sun, L

Antitumor agents. 141. Synthesis and biological evaluation of novel thiocolchicine analogs: N-acyl-, N-aroyl-, and N-(substituted benzyl)deacetylthiocolchicines as potent cytotoxic and antimitotic compounds. [electronic resource] - Journal of medicinal chemistry May 1993 - 1474-9 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.

0022-2623

10.1021/jm00062a021 doi


Antineoplastic Agents--chemical synthesis
Circular Dichroism
Colchicine--analogs & derivatives
Humans
Structure-Activity Relationship
Tubulin--drug effects
Tumor Cells, Cultured--drug effects