The human prointerleukin 1 beta gene requires DNA sequences both proximal and distal to the transcription start site for tissue-specific induction. [electronic resource]
- Molecular and cellular biology Mar 1993
- 1332-44 p. digital
Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
0270-7306
10.1128/mcb.13.3.1332-1344.1993 doi
Animals Base Sequence CCAAT-Enhancer-Binding Proteins Chloramphenicol O-Acetyltransferase--biosynthesis DNA Mutational Analysis DNA-Binding Proteins--pharmacology Enhancer Elements, Genetic--genetics Fibroblasts--cytology Gene Expression Regulation Genes HeLa Cells Humans Interleukin-1--biosynthesis Lipopolysaccharides--pharmacology Mice Molecular Sequence Data Monocytes--cytology Nuclear Proteins--pharmacology Protein Precursors--biosynthesis Recombinant Proteins--biosynthesis Regulatory Sequences, Nucleic Acid--genetics Tetradecanoylphorbol Acetate--pharmacology Transcription Factors--metabolism Transcription, Genetic--drug effects Transcriptional Activation Transfection