Pseudomonas exotoxin conjugated to monoclonal antibody MRK16 specifically kills multidrug resistant cells in cultured renal carcinomas and in MDR-transgenic mice. [electronic resource]
- The Journal of urology Jan 1993
- 174-8 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0022-5347
10.1016/s0022-5347(17)36033-0 doi
ADP Ribose Transferases Animals Antibodies, Monoclonal--therapeutic use Bacterial Toxins--pharmacology Carcinoma, Renal Cell--drug therapy Drug Resistance Exotoxins--pharmacology Humans Immunotoxins--pharmacology Kidney Neoplasms--drug therapy Male Mice Mice, Transgenic Prostatic Neoplasms--drug therapy Tumor Cells, Cultured--drug effects Virulence Factors Pseudomonas aeruginosa Exotoxin A