Ioannides, C <br/><br/>
The mutagenicity and interactions of 2- and 4-(acetylamino)fluorene with cytochrome P450 and the aromatic hydrocarbon receptor may explain the difference in their carcinogenic potency.  [electronic resource] 

 -  Chemical research in toxicology   
 - 535-41 p.  digital 
<br/><br/> Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>0893-228X 
<br/><br/><label>Standard No.: </label>10.1021/tx00034a023  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>2-Acetylaminofluorene--analogs & derivatives<br/>Animals<br/>Aroclors--pharmacology<br/>Binding, Competitive--drug effects<br/>Carcinogens--chemistry<br/>Chlorodiphenyl (54% Chlorine)<br/>Cytochrome P-450 Enzyme System--biosynthesis<br/>Cytosol--drug effects<br/>Enzyme Induction--drug effects<br/>Immunoblotting<br/>In Vitro Techniques<br/>Isomerism<br/>Male<br/>Microsomes, Liver--drug effects<br/>Mutagenicity Tests<br/>Mutagens--toxicity<br/>Polychlorinated Dibenzodioxins--metabolism<br/>Rats<br/>Rats, Wistar<br/>Receptors, Aryl Hydrocarbon<br/>Receptors, Drug--drug effects