Monge, A <br/><br/>
A novel class of cardiotonic agents: synthesis and biological evaluation of pyridazino[4,5-b]indoles with cyclic AMP phosphodiesterases inhibiting properties.  [electronic resource] 

 -  Journal of pharmaceutical sciences  May 1993 
 - 526-30 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>0022-3549 
<br/><br/><label>Standard No.: </label>10.1002/jps.2600820519  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>3',5'-Cyclic-AMP Phosphodiesterases--antagonists & inhibitors<br/>Animals<br/>Aorta, Thoracic--drug effects<br/>Blood Platelets--drug effects<br/>Cardiotonic Agents--chemical synthesis<br/>Dogs<br/>Female<br/>Guinea Pigs<br/>Heart--drug effects<br/>Humans<br/>In Vitro Techniques<br/>Indoles--chemical synthesis<br/>Isoenzymes--antagonists & inhibitors<br/>Male<br/>Myocardium--enzymology<br/>Phosphodiesterase Inhibitors--pharmacology<br/>Platelet Aggregation--drug effects<br/>Platelet Aggregation Inhibitors--chemical synthesis<br/>Pyridazines--chemical synthesis<br/>Rats<br/>Rats, Wistar<br/>Structure-Activity Relationship