TY - GEN AU - Kuo,S C AU - Lee,H Z AU - Juang,J P AU - Lin,Y T AU - Wu,T S AU - Chang,J J AU - Lednicer,D AU - Paull,K D AU - Lin,C M AU - Hamel,E TI - Synthesis and cytotoxicity of 1,6,7,8-substituted 2-(4'-substituted phenyl)-4-quinolones and related compounds: identification as antimitotic agents interacting with tubulin SN - 0022-2623 PY - 1993///0609 KW - Animals KW - Antineoplastic Agents KW - chemical synthesis KW - Humans KW - Intestinal Neoplasms KW - drug therapy KW - Leukemia L1210 KW - Leukemia P388 KW - Lung Neoplasms KW - Melanoma KW - Mice KW - Molecular Structure KW - Nasopharyngeal Neoplasms KW - Quinolines KW - Quinolones KW - Software KW - Structure-Activity Relationship KW - Tubulin KW - metabolism KW - Tubulin Modulators KW - Tumor Cells, Cultured N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1021/jm00061a005 ER -