Human papillomavirus 16 E6 expression disrupts the p53-mediated cellular response to DNA damage. [electronic resource]
- Proceedings of the National Academy of Sciences of the United States of America May 1993
- 3988-92 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
0027-8424
10.1073/pnas.90.9.3988 doi
Cell Cycle--drug effects Cells, Cultured Cervix Uteri--cytology DNA Damage DNA Replication--drug effects DNA, Viral--analysis Dactinomycin--pharmacology Epithelial Cells Epithelium--metabolism Female G1 Phase Genes, p53 HeLa Cells Humans Keratinocytes--cytology Male Oncogene Proteins, Viral--genetics Open Reading Frames Papillomaviridae--drug effects Polymerase Chain Reaction--methods RNA, Messenger--genetics RNA, Viral--analysis Repressor Proteins Restriction Mapping Transfection Tumor Cells, Cultured Tumor Suppressor Protein p53--genetics Uterine Cervical Neoplasms--microbiology