TY - GEN AU - Robinson,M J AU - Corbett,A H AU - Osheroff,N TI - Effects of topoisomerase II-targeted drugs on enzyme-mediated DNA cleavage and ATP hydrolysis: evidence for distinct drug interaction domains on topoisomerase II SN - 0006-2960 PY - 1993///0513 KW - Adenosine Triphosphate KW - metabolism KW - Amsacrine KW - pharmacology KW - Animals KW - Anti-Infective Agents KW - Antineoplastic Agents KW - Binding Sites KW - Cell Nucleus KW - enzymology KW - DNA Topoisomerases, Type II KW - chemistry KW - DNA, Bacterial KW - Drosophila melanogaster KW - Escherichia coli KW - genetics KW - Etoposide KW - Fluoroquinolones KW - Genistein KW - Hydrolysis KW - Isoflavones KW - Novobiocin KW - Plasmids KW - Quercetin KW - analogs & derivatives KW - Quinolones KW - Topoisomerase II Inhibitors N1 - Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1021/bi00065a016 ER -