TY  - GEN
AU  - Sircar,I
AU  - Hodges,J C
AU  - Quin,J
AU  - Bunker,A M
AU  - Winters,R T
AU  - Edmunds,J J
AU  - Kostlan,C R
AU  - Connolly,C
AU  - Kesten,S J
AU  - Hamby,J M
TI  - Nonpeptide angiotensin II receptor antagonists. 2. Design, synthesis, and structure-activity relationships of 2-alkyl-4-(1H-pyrrol-1-yl)-1H-imidazole derivatives: profile of 2-propyl-1-[[2'-(1H-tetrazol-5-yl)-[1,1' -biphenyl]-4-yl]-methyl]-4-[2-(trifluoroacetyl)-1H-pyrrol-1-yl]-1H- imidazole-5-carboxylic acid (CI-996)
SN  - 0022-2623
PY  - 1993///0924
KW  - Angiotensin Receptor Antagonists
KW  - Animals
KW  - Aorta
KW  - Disease Models, Animal
KW  - GABA Antagonists
KW  - Hypertension, Renal
KW  - prevention & control
KW  - Liver
KW  - metabolism
KW  - Male
KW  - Muscle Contraction
KW  - drug effects
KW  - Pyridines
KW  - administration & dosage
KW  - Rabbits
KW  - Rats
KW  - Rats, Sprague-Dawley
KW  - Receptors, Angiotensin
KW  - chemistry
KW  - Structure-Activity Relationship
KW  - gamma-Aminobutyric Acid
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1021/jm00068a002
ER  -