TY  - GEN
AU  - Stein,P D
AU  - Hunt,J T
AU  - Floyd,D M
AU  - Moreland,S
AU  - Dickinson,K E
AU  - Mitchell,C
AU  - Liu,E C
AU  - Webb,M L
AU  - Murugesan,N
AU  - Dickey,J
TI  - The discovery of sulfonamide endothelin antagonists and the development of the orally active ETA antagonist 5-(dimethylamino)-N-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulf onamide
SN  - 0022-2623
PY  - 1994///0315
KW  - Animals
KW  - Antihypertensive Agents
KW  - chemical synthesis
KW  - Cell Line
KW  - Dansyl Compounds
KW  - Endothelin Receptor Antagonists
KW  - Endothelins
KW  - metabolism
KW  - Hypertension
KW  - drug therapy
KW  - Molecular Structure
KW  - Muscle, Smooth, Vascular
KW  - drug effects
KW  - Rabbits
KW  - Rats
KW  - Structure-Activity Relationship
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1021/jm00029a001
ER  -