Rowley, M <br/><br/>
3-Acyl-4-hydroxyquinolin-2(1H)-ones. Systemically active anticonvulsants acting by antagonism at the glycine site of the N-methyl-D-aspartate receptor complex.  [electronic resource] 

 -  Journal of medicinal chemistry  Oct 1993 
 - 3386-96 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>0022-2623 
<br/><br/><label>Standard No.: </label>10.1021/jm00074a020  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Acylation<br/>Animals<br/>Anticonvulsants--chemical synthesis<br/>Binding Sites<br/>Cerebral Cortex--metabolism<br/>Glycine--metabolism<br/>Hydroxyquinolines--chemical synthesis<br/>Ketones--chemical synthesis<br/>Kinetics<br/>Lactams--chemical synthesis<br/>Rats<br/>Rats, Inbred Strains<br/>Receptors, N-Methyl-D-Aspartate--antagonists & inhibitors<br/>Structure-Activity Relationship