TY  - GEN
AU  - Ciosek,C P
AU  - Magnin,D R
AU  - Harrity,T W
AU  - Logan,J V
AU  - Dickson,J K
AU  - Gordon,E M
AU  - Hamilton,K A
AU  - Jolibois,K G
AU  - Kunselman,L K
AU  - Lawrence,R M
TI  - Lipophilic 1,1-bisphosphonates are potent squalene synthase inhibitors and orally active cholesterol lowering agents in vivo
SN  - 0021-9258
PY  - 1993///1220
KW  - Administration, Oral
KW  - Animals
KW  - Anticholesteremic Agents
KW  - pharmacology
KW  - Cholesterol
KW  - biosynthesis
KW  - Coenzymes
KW  - Cricetinae
KW  - Diphosphonates
KW  - administration & dosage
KW  - Dolichols
KW  - metabolism
KW  - Farnesyl-Diphosphate Farnesyltransferase
KW  - antagonists & inhibitors
KW  - Humans
KW  - Lovastatin
KW  - Male
KW  - Mesocricetus
KW  - Microsomes, Liver
KW  - enzymology
KW  - Rats
KW  - Rats, Sprague-Dawley
KW  - Squalene
KW  - Ubiquinone
KW  - analogs & derivatives
N1  - Publication Type: Journal Article
ER  -