TY - GEN AU - Knab,A M AU - Fertala,J AU - Bjornsti,M A TI - Mechanisms of camptothecin resistance in yeast DNA topoisomerase I mutants SN - 0021-9258 PY - 1993///1201 KW - Amino Acid Sequence KW - Base Sequence KW - Camptothecin KW - toxicity KW - Chromatography KW - Chromatography, Affinity KW - Chromatography, Ion Exchange KW - DNA Topoisomerases, Type I KW - genetics KW - Drug Resistance, Microbial KW - Durapatite KW - Humans KW - Molecular Sequence Data KW - Molecular Weight KW - Mutagenesis, Site-Directed KW - Oligodeoxyribonucleotides KW - Plasmids KW - Point Mutation KW - Restriction Mapping KW - Saccharomyces cerevisiae KW - drug effects KW - Sequence Homology, Amino Acid KW - Substrate Specificity KW - Tyrosine N1 - Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S ER -