Mechanisms of camptothecin resistance in yeast DNA topoisomerase I mutants. [electronic resource]
- The Journal of biological chemistry Oct 1993
- 22322-30 p. digital
Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
0021-9258
Amino Acid Sequence Base Sequence Camptothecin--toxicity Chromatography Chromatography, Affinity Chromatography, Ion Exchange DNA Topoisomerases, Type I--genetics Drug Resistance, Microbial--genetics Durapatite Humans Molecular Sequence Data Molecular Weight Mutagenesis, Site-Directed Oligodeoxyribonucleotides Plasmids Point Mutation Restriction Mapping Saccharomyces cerevisiae--drug effects Sequence Homology, Amino Acid Substrate Specificity Tyrosine