TY  - GEN
AU  - Xiang,J
AU  - Chen,Z
AU  - Delbaere,L T
AU  - Liu,E
TI  - Differences in antigen-binding affinity caused by a single amino acid substitution in the variable region of the heavy chain
SN  - 0818-9641
PY  - 1993///1216
KW  - Amino Acid Sequence
KW  - Antibody Affinity
KW  - Antigens, Neoplasm
KW  - immunology
KW  - Base Sequence
KW  - Binding Sites, Antibody
KW  - Blotting, Western
KW  - Electrophoresis, Polyacrylamide Gel
KW  - Enzyme-Linked Immunosorbent Assay
KW  - Gene Expression
KW  - Histidine
KW  - genetics
KW  - Humans
KW  - Hybridomas
KW  - Immunoglobulin Heavy Chains
KW  - Immunoglobulin Variable Region
KW  - Molecular Sequence Data
KW  - Mutagenesis, Site-Directed
KW  - Recombinant Fusion Proteins
KW  - metabolism
KW  - Structure-Activity Relationship
KW  - Tumor Cells, Cultured
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1038/icb.1993.28
ER  -