Xiang, J <br/><br/>
Differences in antigen-binding affinity caused by a single amino acid substitution in the variable region of the heavy chain.  [electronic resource] 

 -  Immunology and cell biology  Aug 1993 
 - 239-47 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>0818-9641 
<br/><br/><label>Standard No.: </label>10.1038/icb.1993.28  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Amino Acid Sequence<br/>Antibody Affinity<br/>Antigens, Neoplasm--immunology<br/>Base Sequence<br/>Binding Sites, Antibody<br/>Blotting, Western<br/>Electrophoresis, Polyacrylamide Gel<br/>Enzyme-Linked Immunosorbent Assay<br/>Gene Expression<br/>Histidine--genetics<br/>Humans<br/>Hybridomas--immunology<br/>Immunoglobulin Heavy Chains--genetics<br/>Immunoglobulin Variable Region--genetics<br/>Molecular Sequence Data<br/>Mutagenesis, Site-Directed<br/>Recombinant Fusion Proteins--metabolism<br/>Structure-Activity Relationship<br/>Tumor Cells, Cultured