TY  - GEN
AU  - Ashton,M J
AU  - Cook,D C
AU  - Fenton,G
AU  - Karlsson,J A
AU  - Palfreyman,M N
AU  - Raeburn,D
AU  - Ratcliffe,A J
AU  - Souness,J E
AU  - Thurairatnam,S
AU  - Vicker,N
TI  - Selective type IV phosphodiesterase inhibitors as antiasthmatic agents. The syntheses and biological activities of 3-(cyclopentyloxy)-4-methoxybenzamides and analogues
SN  - 0022-2623
PY  - 1994///0707
KW  - 3',5'-Cyclic-AMP Phosphodiesterases
KW  - antagonists & inhibitors
KW  - Animals
KW  - Aorta
KW  - enzymology
KW  - Asthma
KW  - drug therapy
KW  - Benzamides
KW  - chemical synthesis
KW  - Bronchial Spasm
KW  - chemically induced
KW  - Eosinophils
KW  - drug effects
KW  - Guinea Pigs
KW  - Histamine
KW  - pharmacology
KW  - Isoenzymes
KW  - Kinetics
KW  - Male
KW  - Molecular Structure
KW  - Phosphodiesterase Inhibitors
KW  - Pyridines
KW  - Structure-Activity Relationship
KW  - Superoxides
KW  - metabolism
KW  - Swine
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1021/jm00037a021
ER  -