Frim, D M

Implanted fibroblasts genetically engineered to produce brain-derived neurotrophic factor prevent 1-methyl-4-phenylpyridinium toxicity to dopaminergic neurons in the rat. [electronic resource] - Proceedings of the National Academy of Sciences of the United States of America May 1994 - 5104-8 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.

0027-8424

10.1073/pnas.91.11.5104 doi


1-Methyl-4-phenylpyridinium--antagonists & inhibitors
Animals
Brain-Derived Neurotrophic Factor
Cell Line
Cell Survival
Cells, Cultured
Fibroblasts--metabolism
Genetic Engineering
Male
Nerve Degeneration
Nerve Growth Factors--genetics
Nerve Tissue Proteins--genetics
Neurons--drug effects
Rats
Rats, Sprague-Dawley
Receptors, Dopamine--drug effects
Substantia Nigra--drug effects