TY  - GEN
AU  - D'Amato,R J
AU  - Lin,C M
AU  - Flynn,E
AU  - Folkman,J
AU  - Hamel,E
TI  - 2-Methoxyestradiol, an endogenous mammalian metabolite, inhibits tubulin polymerization by interacting at the colchicine site
SN  - 0027-8424
PY  - 1994///0601
KW  - 2-Methoxyestradiol
KW  - Animals
KW  - Binding, Competitive
KW  - Cattle
KW  - Colchicine
KW  - metabolism
KW  - Estradiol
KW  - analogs & derivatives
KW  - Glutamates
KW  - pharmacology
KW  - In Vitro Techniques
KW  - Microscopy, Electron
KW  - Microtubules
KW  - drug effects
KW  - Polymers
KW  - Structure-Activity Relationship
KW  - Tubulin
N1  - Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1073/pnas.91.9.3964
ER  -