TY  - GEN
AU  - Rezaie,A R
AU  - Esmon,C T
TI  - Conversion of glutamic acid 192 to glutamine in activated protein C changes the substrate specificity and increases reactivity toward macromolecular inhibitors
SN  - 0021-9258
PY  - 1993///1020
KW  - Amino Acid Sequence
KW  - Animals
KW  - Base Sequence
KW  - Cattle
KW  - DNA
KW  - Electrophoresis, Polyacrylamide Gel
KW  - Enzyme Activation
KW  - Factor Va
KW  - antagonists & inhibitors
KW  - Factor X
KW  - metabolism
KW  - Glutamates
KW  - Glutamic Acid
KW  - Glutamine
KW  - Humans
KW  - Kinetics
KW  - Molecular Sequence Data
KW  - Molecular Weight
KW  - Mutagenesis, Site-Directed
KW  - Oligodeoxyribonucleotides
KW  - Oligonucleotides, Antisense
KW  - Protein C
KW  - biosynthesis
KW  - Prothrombin
KW  - Receptors, Cell Surface
KW  - Receptors, Thrombin
KW  - Recombinant Proteins
KW  - Substrate Specificity
KW  - Thrombin
N1  - Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S
ER  -