Mignot, E

Heterozygosity at the canarc-1 locus can confer susceptibility for narcolepsy: induction of cataplexy in heterozygous asymptomatic dogs after administration of a combination of drugs acting on monoaminergic and cholinergic systems. [electronic resource] - The Journal of neuroscience : the official journal of the Society for Neuroscience Mar 1993 - 1057-64 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.

0270-6474


Aging--physiology
Animals
Azepines--pharmacology
Biogenic Amines--pharmacology
Brain--drug effects
Cataplexy--chemically induced
Chromosome Mapping
Crosses, Genetic
Dog Diseases--genetics
Dogs
Dopamine Agents--pharmacology
Ergolines--pharmacology
Female
Genes, Recessive
Genetic Predisposition to Disease
Heterozygote
Humans
Male
Narcolepsy--genetics
Parasympathomimetics--pharmacology
Pedigree
Physostigmine--pharmacology
Prazosin--pharmacology
Quinpirole
Sleep--drug effects