Schlesinger, M J

An in-frame insertion into the Sindbis virus 6K gene leads to defective proteolytic processing of the virus glycoproteins, a trans-dominant negative inhibition of normal virus formation, and interference in virus shut off of host-cell protein synthesis. [electronic resource] - Virology Mar 1993 - 424-32 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0042-6822

10.1006/viro.1993.1139 doi


Amino Acid Sequence
Animals
Cells, Cultured
Chick Embryo
Cricetinae
Culicidae
Genes, Viral--genetics
Glycoproteins--genetics
Molecular Sequence Data
Mutagenesis, Insertional
Protein Biosynthesis
Protein Processing, Post-Translational--genetics
Sindbis Virus--genetics
Viral Proteins--genetics
Virion--chemistry