Cleavage of the epidermal growth factor receptor by a membrane-bound leupeptin-sensitive protease active in nonionic detergent lysates of senescent but not young human diploid fibroblasts. [electronic resource]
- Journal of cellular physiology Sep 1994
- 427-34 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
0021-9541
10.1002/jcp.1041600305 doi
Cell Line Cell Membrane--metabolism Cellular Senescence Detergents Diploidy Endopeptidases--metabolism ErbB Receptors--chemistry Fibroblasts--metabolism Humans Intracellular Membranes--metabolism Leupeptins--pharmacology Ligands Phosphorylation Protease Inhibitors--pharmacology Protein Processing, Post-Translational Solvents--pharmacology Stimulation, Chemical Trypsin--pharmacology